This book presents, in a mechanistic, quantitative manner, many of the necessary
fundamentals required for pharmaceutics-related problems. It can be used to guide
students and professionals until they understand the fundamentals well enough to
focus their research areas and read articles in the literature. This book has evolved
from several course notes at Temple University School of Pharmacy, particularly
with the aid of books by J. R. Barrante (Physical Chemistry for the Life Sciences),
R. Chang (Physical Chemistry with Applications to Biological Systems), A. T. Florence
and D. Attwood (Physicochemical Principles of Pharmacy), A. Martin (Physical
Pharmacy), O. Robbins, Jr. (Ionic Reactions and Equilibria), and Williams et
al. (Basic Physical Chemistry for the Life Sciences). It is intended primarily for
graduate students in pharmaceutics. This book can be taught in two semesters with
supplemental material: Chapters 1 to 4 for the first semester and Chapters 5 to 7 for
the second semester. I hope that this book will also be useful as a reference for
pharmaceutical scientists engaged in drug product development.
This text is designed to guide the student pharmacist or pharmacy technician through the main
stages involved in pharmaceutical dispensing. The purpose of the book is to provide students with
a core reference text to accompany the compulsory dispensing courses found in all undergraduate
MPharm programmes and equivalent technical training courses.
Christopher A Langley
Birmingham, United Kingdom
Throughout her ministry Ellen White devoted much effort and thought to alleviating the sorrows of the sick and suffering and to pointing them to the Great Physician who is able to heal to the uttermost—both physically and spiritually.
This volume brings together the counsels Ellen White received on this topic during seven decades. Topics include Essentials to Health, Diet and Health, Outdoor Life and Physical Activity, Teaching Health Principles, and Holiness of Life—as well as practical advice for doctors, nurses, and others who are engaged in healthcare.
The handsome binding is durable, strong, and a great addition to the Christian Home Library series.
This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. It was not my intention to write a popular book; what distinguishes this one from many others on the same subject is its large use of algebra and calculus. For this I make no apologies; in fact a serious study of pharmacokinetics without the help of mathematics is, in my opinion, impossible. The exact definition of many pharmacokinetic quantities, even the most common, and the correct use of many equations, even the most simple, requires the constant use of mathematical language. On the other hand I have made a considerable effort to use only elementary algebra and elementary calculus, as commonly taught in most introductory university courses. For the few exceptions, when less common mathematical concepts were needed, I have supplied the necessary explanations in four appendices. The first three chapters are a general introduction to the scientific method. Chapters 4 to 12 show different specific methods to deal with pharmacokinetic pr- lems. There is considerable overlap among those chapters; this is intentional and its p- pose is to convince the reader that every problem can be solved in more than one way, including ways that were not mentioned in this book and that intelligent readers can find for their own pleasure. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured
The connection between inflammation and heart disease, arthritis, and other chronic ailments has become increasingly clear. Many food allergies and poor dietary choices over stimulate the immune system and cause inflammatory responses that erode the body’s wellness and pave the path for ill health. Based on her naturopathic practice, Jessica Black has devised a complete program for how to eat and cook to minimize and even prevent inflammation and its consequences. The first part of the book explains the benefits of the anti-inflammatory diet with an accessible discussion of the science behind it. The second half contains 108 recipes. The author offers many substitution suggestions and includes a healthy ingredient tip with each recipe. Most of the dishes can be prepared quickly and easily by even novice cooks. A week of sample menus for summer months and another for winter are included, as well as a substitutions chart, allowing readers to modify their favorite recipes to increase their healing potential.
A guide for younger R&D chemists as to how they can quickly evolve skills built around three factors -- people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organizational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job. As such, it teaches the vital managerial aspects of scientific jobs in industry, which are not taught at university, providing a deep and detailed insight into the intricacies of managing research.
The text is divided neatly into four sections:
* Harnessing the Human Resource
* Organising for an Innovative Environment
* Creativity and Innovation
* Project Management of Innovation
The author, Peter Bamfield, is now working as a consultant. Due to his long experience in the chemical industry, he was elected President of the Royal Society of Chemistry's Industrial Affairs Division, and thus has a profound first-hand view of staff, companies and organizations in and around the industry.
This third edition has been revised and updated to take into account global developments and recent changes in regulatory affairs
A didactic, illustrated guide to the use of ultrasound as a diagnostic tool in clinical practice. Prepared by an international group of experts with wide experience in both developed and developing countries, the manual responds to the need for a basic reference text that can help doctors, sonographers, nurses, and midwives solve imaging problems when no experts are available. With this need in mind, the manual adopts a practical approach aimed at providing a thorough grounding in both the techniques of ultrasound and the interpretation of images. The need for extensive supervised training is repeatedly emphasized. Because the clinical value of ultrasound depends so greatly on the experience and skill of the operator, the manual makes a special effort to alert readers to common pitfalls and errors, and to indicate specific clinical situations where ultrasound may not be helpful or reliable as a diagnostic tool. Explanatory text is supported by numerous practical tips, warnings, checklists and over 600 illustrations. The opening chapters explain how ultrasound works, outline the factors to consider when choosing a scanner, and introduce the basic rules of scanning, including advice on how to recognize and interpret artefacts. Guidance on the selection of ultrasound equipment includes clear advice concerning where costs can be spared and where investment is essential. The core of the manual consists of seventeen chapters providing guidance on scanning techniques and the interpretation of images for specific organs and anatomical sites, with the most extensive chapter devoted to obstetrics. Each chapter contains illustrated information on indications for scanning, preparation of the patient, including choice of transducer and setting of the correct gain, general scanning techniques, and specific techniques for identifying anatomical landmarks and recognizing abnormalities. The manual concludes with WHO specifications for a general-purpose scanner judged entirely suitable for 90-95% of the most common ultrasound examinations.
The faculty will strive to provide opportunities for students to build upon
principles and skills taught in the classroom and laboratory. The nursing process
will be utilized as an integral part of guidelines for nursing practice.
The faculty believes that students have a fundamental responsibility to provide
care to all clients assigned to them and that refusal to care for clients, including
clients with blood-transmitted diseases, conflicts with the ethics of the nursing
profession. We believe nursing professionals have a moral commitment to clients
and a special responsibility to exemplify the standards of ethical behavior. The
faculty will provide intensive education and counseling when students feel
apprehensive or have concerns regarding client assignments.
Clinical supervision and planned instruction will be provided by a faculty member
while in the clinical setting. The student has the responsibility to use initiative and
self-direction in making the most of their clinical opportunities to gain greater
understanding, knowledge, and experiences in all nursing areas.
The major portion of clinical experiences will be in the following areas: medicalsurgical;
obstetrical; and pediatrics. Limited clinical experience will be provided in
these areas: mental health units, operating room, emergency room, critical care,
nursing homes, and community agencies. Pharmacology and Diet Therapy will be
integrated throughout each area.
The easiest and most trusted way to learn the clinical application of pharmacokinetics
5 STAR DOODY'S REVIEW!
"This is an important reference that teaches clinically relevant pharmacokinetic dosing and therapeutic drug monitoring tools. This second edition includes updated information on dosing immunosuppressants, as well as dosing concepts in pediatric and hemodialysis patients. The book is intended as an instructive tool in pharmacokinetics for healthcare practitioners who wish to learn these concepts and apply them in their clinical practice. The book satisfies its objectives, outlining important pharmacokinetic concepts in an organized and easy to understand fashion. It is also written by a pharmacist with extensive experience in pharmacokinetics and includes clinically pertinent pearls for individual drugs.
The suspension dosage form has long been used for poorly soluble active ingre- ents for various therapeutic indications. Development of stable suspensions over the shelf life of the drug product continues to be a challenge on many fronts. A good understanding of the fundamentals of disperse systems is essential in the development of a suitable pharmaceutical suspension. The development of a s- pension dosage form follows a very complicated path. The selection of the proper excipients (surfactants, viscosity imparting agents etc.) is important. The particle size distribution in the finished drug product dosage form is a critical parameter that significantly impacts the bioavailability and pharmacokinetics of the product. Appropriate analytical methodologies and instruments (chromatographs, visco- ters, particle size analyzers, etc.) must be utilized to properly characterize the s- pension formulation. The development process continues with a successful scale-up of the manufacturing process. Regulatory agencies around the world require cli- cal trials to establish the safety and efficacy of the drug product. All of this devel- ment work should culminate into a regulatory filing in accordance with the regulatory guidelines. Pharmaceutical Suspensions, From Formulation Development to Manufacturing, in its organization, follows the development approach used widely in the pharmaceutical industry. The primary focus of this book is on the classical disperse system – poorly soluble active pharmaceutical ingredients s- pended in a suitable vehicle.
Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control presents that latest information on protecting pharmaceutical and healthcare products from spoilage by microorganisms, and protecting patients and consumers. With both sterile and non-sterile products, the effects can range from discoloration to the potential for fatality.
The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.
Contains the applications of pharmaceutical microbiology in sterile and non-sterile products
Presents the practical aspects of pharmaceutical microbiology testing
Provides contamination control risks and remediation strategies, along with rapid microbiological methods
Includes bioburden, endotoxin, and specific microbial risks
Highlights relevant case studies and risk assessment scenarios
As of May 2013, 93 children previously diagnosed with regressive autism were able to shed their autism diagnosis, their symptoms, and return to an overall state of health and vitality using the protocols revealed in this book. Kerri Rivera has outlined a very complete approach to autism recovery that includes an understanding of the importance of Biofilm theory and protocol. She recommends safe interventions that do no harm, and are helping to confront a growing epidemic. Kerri Rivera's approach includes common sense dietary recommendations, the use of supplements to restore balance to the body and immune system, as well as mild oxidative therapies to address chronic infection and inflammation. She has taken children who were in the throes of autism (meaning chronic illness) to healing. The symptoms being labeled as autism are fading away, the children are talking and socializing, and their ATEC scores prove beyond a shadow of a doubt what their parents are claiming: their children no longer have autism. Kerri Rivera's grasp of a biomedical approach to Autism recovery, paired with her passion for service has allowed families of all socioeconomic backgrounds to have what they might never have otherwise found: a means by which to help their children. This book contains over 120 testimonials from parents (and some of the children themselves) describing their journey and resulting success.
Modern Pharmaceutical Drug Analysis essentially involves as a necessary integral component
even greater horizons than the actual prevalent critical analysis of not only the active pharmaceutical
substances but also the secondary pharmaceutical product(s) i.e., the dosage forms having either
single or multi-component formulated product. The fundamental reasons for this sudden legitimate
surge in the newer evolving methodologies in the ‘analysis of drug substances’ are perhaps due to
the tremendous growth in the progress of ‘medicinal chemistry’ towards achieving one ultimate
objective which is to obtain ‘better drugs for a better world’.
With the advent of computer-aided-drug modeling (CADM) the critical, scientific and faster
approach to newer drug entities based on the biologically active prototypes, combinatorial chemistry,
chiral chemistry and biotechnology has paved the way towards more specific, potent and above
all less toxic ‘drugs’ to improve the ultimate quality of life in humans.
Keeping in view the above astronomical growth in the design of complicated, specific and
highly active drug molecules an equally viable, rigorous, accurate and precise analytical methods
have been evolved with the passage of time which have now occupied pivotal and vital positions in
most of the Official Compendia viz., USP, BP, Int.P., Eur. P, IP etc., for the analysis of such
compounds both in pure and dosage forms.
A handbook that you will refer to throughout your entire pharmacy education!
A Doody's Core Title for 2015!
Pharmacy Student Survival Guide is a one-of-a-kind roadmap for excelling in pharmacy practice courses. A unique combination calculations, kinetics, drug information, medical terminology, and laboratory data book all in one, the Guide helps you organize case information, improve problem-solving skills, learn terminology, and impress faculty during rounds.
Pharmacy Student Survival Guide is presented in three sections that span the entire pharmacy curriculum:
Systems and Expectations covering etiquette, ethics, communication, monitoring patients, and the function of a medical team
Patient Care Tool Box covering medical terminology, pharmacokinetics, laboratory data, and physical assessment
Topics in Pharmacy Practice addressing the practice of community and institutional pharmacy, the pharmacists as drug information specialist, managed care, public health, and global pharmacy
Valuable for both introductory and advanced practice courses, Pharmacy Student Survival Guide is the one book every pharmacy student must own
This book concentrates on the analytical aspects of drug development and manufacture, focusing on the analysis of the active ingredient or drug substance. It provides those joining the industry or other areas of pharmaceutical research with a source of reference to a broad range of techniques and their applications, allowing them to choose the most appropriate analytical technique for a particular purpose.
Table of Contents:
Quality Control and Regulation
Development of Achiral Separation Methods in Pharmaceutical Analysis
Chiral Analysis of Pharmaceuticals
Nuclear Magnetic Resonance Spectroscopy in Pharmaceutical Analysis
Mass Spectrometry in Pharmaceutical Analysis
Vibrational Spectroscopy in Pharmaceutical Analysis
Solid-State Analysis and Polymorphism
Microscopy and Imaging in Pharmaceutical Analysis
Process Analysis in the Pharmaceutical Industry
"This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student…the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read."–Journal of Chemical Biology, May 2009
Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules).
Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life,with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity.Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry.
An invaluable revision aid for those preparing for multiple choice questions in clinical pharmacy. Questions in this textbook are practice-oriented and are intended to assess students' knowledge of clinical issues, evaluative and analytical skills, and ability to apply their knowledge in clinical practice. Topics covered include: * Therapeutics and rational drug use * Aetiology of disease states * Presentation of conditions * Investigations and diagnostic testing * Drug therapy including adverse drug reactions * Drug interactions * Contra-indications The questions are presented as four practice tests, each consisting of 80 MCQs presented in a variety of formats. MCQs in Clinical Pharmacy is an indispensable aid for anyone preparing to sit a multiple choice question examination in pharmacy and for those carrying out a self-evaluation exercise for continuing professional development
Communication Skills in Pharmacy Practice helps pharmacy and pharmacy technician students learn the principles, skills, and practices that are the foundation for clear communication and the essential development of trust with future patients. This text's logical organization guides students from theory and basic principles to practical skills development to the application of those skills in everyday encounters. Sample dialogues show students how to effectively communicate, and practical exercises fine tune their communication skills in dealing with a variety of sensitive situations that arise in pharmacy practice.
A practical and evidence-based guide for student, pre-registration and qualified pharmacists
Symptoms in the Pharmacy is an indispensable guide to the management of common symptoms seen in the pharmacy. With advice from an author team that includes both pharmacists and GPs, the book covers ailments which will be encountered in the pharmacy on a daily basis.
Now in its sixth edition Symptoms in the Pharmacy has been fully revised to reflect the latest evidence and availability of new medicines. There are new sections and case studies for 'POM' to 'P' switches including chloramphenicol, sumatriptan, diclofenac, naproxen and amorolfine. This edition features colour photographs of skin conditions for the first time enabling the differentiation and diagnosis of common complaints. The public health and illness prevention content have been expanded to support this increasingly important aspect of the pharmacist’s work.
The book is designed for quick and easy reference with separate chapters for each ailment. Each chapter incorporates a decision making framework in which the information necessary for treatment and suggestions on ‘when to refer’ is distilled into helpful summary boxes. At the end of each chapter there are example case studies providing the view of pharmacists, doctors and patients for most conditions covered. These easy-to-follow- chapters can be read cover to cover or turned to for quick reference. This useful guide should be kept close at hand for frequent consultation.
Frank A. Sloan has been the J. Alexander McMahon Professor of Health Policy
and Management and Professor of Economics at Duke University since 1993,
where he holds faculty appointments in the Department of Economics, the
School of Public Policy, the Fuqua School of Business, and the School of Nursing.
Before joining the faculty at Duke, he was a research economist at the Rand
Corporation and served on the faculties of the University of Florida and Vanderbilt
University. His current research interests include alcohol use and smoking
prevention, long-term care, medical malpractice, and cost-effectiveness analyses
of medical technologies. Professor Sloan also has a long-standing interest in
hospitals, health care financing, and health manpower. He has served on several
national advisory public and private groups, including the Physician Payment
Review Commission. He has been a member of the Institute of Medicine of
the National Academy of Sciences since 1982, recently chairing committees on
vaccine financing and cancer in low- and middle-income countries. He recently
received a Merit Award from the National Institutes of Health and an Investigator
Award from the Robert Wood Johnson Foundation. Professor Sloan’s
most recent books include The Smoking Puzzle: Information, Risk Perceptions,
and Choice (2003) with Drs. V. Kerry Smith and Donald H. Taylor, Jr., and The
Price of Smoking (2004) with Drs. Jan Ostermann, Gabriel Picone, Christopher
Conover, and Donald H. Taylor, Jr